CP-547632

• Target:

  PDGFR|||BTK|||FGFR|||VEGFR

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Angiogenesis

• Purity:

  0.9939

• Bioactivity:

  CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than for EGFR, PDGFR? and related tyrosine kinases (TKs) . PDGFR? and related tyrosine kinases (TKs) CP-547632 has antitumour activity.

• Smiles:

  NC (=O) c1c (NC (=O) NCCCCN2CCCC2) snc1OCc1c (F) cc (Br) cc1F

• Molecular Formula:

  C20H24BrF2N5O3S

• Molecular Weight:

  532.4

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  252003-65-9