CP-547632

• Target :

  PDGFR|||BTK|||FGFR|||VEGFR

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Angiogenesis

• Purity :

  0.9939

• Bioactivity :

  CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than for EGFR, PDGFR? and related tyrosine kinases (TKs) . PDGFR? and related tyrosine kinases (TKs) CP-547632 has antitumour activity.

• Smiles :

  NC(=O)c1c(NC(=O)NCCCCN2CCCC2)snc1OCc1c(F)cc(Br)cc1F

• Molecular Formula :

  C20H24BrF2N5O3S

• Molecular Weight :

  532.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  252003-65-9