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Calmidazolium chloride

CAT: 0931-T10667-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T10667-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
57265-65-3
Target
CaMK, Autophagy
Related Pathways
Neuroscience, Autophagy
Purity
0.9853
Bioactivity
Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist with a Kd of 3 nM, which inhibits CaM-dependent phosphodiesterase (IC50 = 0.15 μM) and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase (IC50 = 0.35 μM) . It also induces apoptosis in certain cancer cell lines.
Smiles
[Cl-].Clc1ccc(cc1)C(c1ccc(Cl)cc1)[n+]1ccn(CC(OCc2ccc(Cl)cc2Cl)c2ccc(Cl)cc2Cl)c1
Molecular Formula
C31H23Cl7N2O
Molecular Weight
687.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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