Products for Research Use Only
RegisterLogin

P2X3 antagonist 34

CAT: 0931-T10560-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T10560-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2417288-67-4
Target
P2X Receptor
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Bioactivity
P2X3 antagonist 34, a potent, selective, and orally active antagonist, targets the P2X3 homotrimeric receptor, exhibiting IC50s of 25 nM, 92 nM, and 126 nM for human, rat, and guinea pig P2X3 receptors respectively. It shows reduced activity against P2X2/3 heterotrimeric receptors across human, rat, and guinea pig models. Notably, this compound demonstrates a significant anti-tussive effect without altering taste[1].
Smiles
CNC(=O)c1cc(F)c(-c2nc3cc(C)ccn3c2C[C@@H]2CCCN(C2)C(=O)OC)c(F)c1
Molecular Formula
C24H26F2N4O3
Molecular Weight
456.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T89459-01P2X3 antagonist 39
T79115-01P2X3 antagonist 38
T63197-01P2X3 antagonist 36
T62400-01P2X3 antagonist 37
T78606-01P2X3-IN-1
T205694-01P2X4 antagonist-3
T87087-01P2X4 antagonist-2
T87086-01P2X4 antagonist-1
T204441-01P2X4 antagonist-4
T62488-01P2X7 receptor antagonist-1

Alternative Products

CatalogName
HY-153710P2X3 antagonist 38
MBS5805871P2X3 antagonist 36
HY-143576P2X3 antagonist 37
HY-161914P2X3 antagonist 39
HY-135976-01P2X3 antagonist 34
217162AF353 (P2X3 Purinergic Receptor Antagonist, AF353, P2X2/3 Purinergic Receptor Antagonist, AF353)
217136A317491 ((S) -5- ((3-phenoxybenzyl) (1,2,3,4-tetrahydronaphthalen-1-yl) carbamoyl) benzene-1,2,4-tricarboxylic Acid, P2X3 Purinergic Receptors Antagonist, A317491, P2X2/3 Purinergic Receptors Antagonist, A317491, A 317491) discontinued
RA10109P2X3
GWB-2AD575P2X3 Antibody
346811-01P2X3 discontinued

Popular Products