Apremilast-d5

• Target:

  PDE|||Apoptosis|||TNF

• Related Pathways:

  Apoptosis|||Metabolism

• Bioactivity:

  Apremilast D5 (CC-10004 D5) is a deuterium-labeled Apremilast. Apremilast is an orally available inhibitor of PDE-4 (IC50: 74 nM) . Apremilast inhibits TNF-? release by lipopolysaccharide (IC50: 104 nM) .

• Smiles:

  [2H]C ([2H]) ([2H]) C ([2H]) ([2H]) Oc1cc (ccc1OC) [C@@H] (CS (C) (=O) =O) N1C (=O) c2cccc (NC (C) =O) c2C1=O

• Molecular Formula:

  C22H24N2O7S

• Molecular Weight:

  465.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1258597-47-5