Apremilast-d5

• Target :

  PDE|||Apoptosis|||TNF

• Related Pathways :

  Apoptosis|||Metabolism

• Bioactivity :

  Apremilast D5 (CC-10004 D5) is a deuterium-labeled Apremilast. Apremilast is an orally available inhibitor of PDE-4 (IC50: 74 nM) . Apremilast inhibits TNF-? release by lipopolysaccharide (IC50: 104 nM) .

• Smiles :

  [2H]C([2H])([2H])C([2H])([2H])Oc1cc(ccc1OC)[C@@H](CS(C)(=O)=O)N1C(=O)c2cccc(NC(C)=O)c2C1=O

• Molecular Formula :

  C22H24N2O7S

• Molecular Weight :

  465.53

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1258597-47-5