Apremilast-d5

CAT: 0931-MF-0004442-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0004442-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1258597-47-5
Target
PDE|||Apoptosis|||TNF
Related Pathways
Apoptosis|||Metabolism
Bioactivity
Apremilast D5 (CC-10004 D5) is a deuterium-labeled Apremilast. Apremilast is an orally available inhibitor of PDE-4 (IC50: 74 nM) . Apremilast inhibits TNF-? release by lipopolysaccharide (IC50: 104 nM) .
Smiles
[2H]C([2H])([2H])C([2H])([2H])Oc1cc(ccc1OC)[C@@H](CS(C)(=O)=O)N1C(=O)c2cccc(NC(C)=O)c2C1=O
Molecular Formula
C22H24N2O7S
Molecular Weight
465.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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