Docetaxel

• Target:

  Microtubule Associated|||Apoptosis|||Endogenous Metabolite

• Related Pathways:

  Apoptosis|||Metabolism|||Cytoskeletal Signaling

• Purity:

  0.9929

• Bioactivity:

  Docetaxel (RP-56976), a semi-synthetic analog of paclitaxel, is a microtubule depolymerization inhibitor (IC50=0.2 ?M) that attenuates the effects of bcl-2 and bcl-xL gene expression and exhibits apoptosis-inducing, anti-tumor activity.

• Smiles:

  O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](O)C(=O)[C@]3(C)[C@@H](O)C[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(OC(C)(C)C)=O)C6=CC=CC=C6)O)=O)C5)[H]

• Molecular Formula:

  C43H53NO14

• Molecular Weight:

  807.88

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  114977-28-5