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Antihistamine-1

CAT: 0931-T10335-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T10335-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1186430-60-3
Target
Cytochromes P450, Potassium Channel, Histamine Receptor
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Neuroscience, Membrane transporter/Ion channel, Metabolism
Purity
>99.99%
Bioactivity
Antihistamine-1 is an H1-antihistamine (Ki: 6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel (IC50s: 5.4 and 0.8 μM) .
Smiles
C(N1C(=NC=2C1=CC=CC2)N3CCC(CC3)N4C=C(C)C=N4)C5=CC=C(F)C=C5
Molecular Formula
C23H24FN5
Molecular Weight
389.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C