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ADU-S100

CAT: 0931-T10252L3Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T10252L3Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1638241-89-0
Target
COX, IκB/IKK, IL Receptor, Others, STING, TNF
Related Pathways
NF-κB, Apoptosis, Immunology/Inflammation, Neuroscience, Others
Purity
0.9983
Bioactivity
ADU-S100 (MIW815) is a cyclic dinucleotide (CDN) class STING agonist that significantly induces the production of IFN-β and pro-inflammatory cytokines TNF-α, IL-6, and MCP-1, induces TBK1 and IRF3 phosphorylation, and exhibits antitumour activity.
Smiles
O[C@H]1[C@]2([H])[C@H](N3C4=NC=NC(N)=C4N=C3)OC1([H])CO[P@@](O[C@]5([H])[C@@](O[C@@H](N6C7=NC=NC(N)=C7N=C6)[C@@H]5O)([H])CO[P@](O2)(S)=O)(S)=O
Molecular Formula
C20H24N10O10P2S2
Molecular Weight
690.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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