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Abeprazan

CAT: 0931-T10221L-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T10221L-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1902954-60-2
Target
Proton pump, Others
Related Pathways
Membrane transporter/Ion channel, Others
Bioactivity
Abeprazan (DWP14012) is a potassium-competitive acid blocker developed as a potential alternative to proton pump inhibitors for treating acid-related diseases. It inhibits H+, K+-ATPase through reversible potassium-competitive ionic binding, without requiring acid activation [1].
Smiles
CNCc1cn(c(c1OC)-c1ccc(F)cc1F)S(=O)(=O)c1cccc(F)c1
Molecular Formula
C19H17F3N2O3S
Molecular Weight
410.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Fexuprazan

Abeprazan is under investigation in clinical trial NCT04341454 (Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Acute or Chronic Gastritis).

CAS Number1902954-60-2
PubChem CID122662112
IUPAC Name1-[5-(2,4-difluorophenyl)-1-(3-fluorophenyl)sulfonyl-4-methoxypyrrol-3-yl]-N-methylmethanamine
Molecular FormulaC19H17F3N2O3S
Molecular Weight410.4
XLogP3.2
Topological Polar Surface Area68.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Heavy Atom Count28
Formal Charge0
Complexity618
SMILES
CNCC1=CN(C(=C1OC)C2=C(C=C(C=C2)F)F)S(=O)(=O)C3=CC=CC(=C3)F
InChI
InChI=1S/C19H17F3N2O3S/c1-23-10-12-11-24(28(25,26)15-5-3-4-13(20)8-15)18(19(12)27-2)16-7-6-14(21)9-17(16)22/h3-9,11,23H,10H2,1-2H3
InChIKey
OUNXGNDVWVPCOL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Fexuprazan
CAS: 1902954-60-2
CID: 122662112
Formula: C19H17F3N2O3S
MW: 410.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight410.4
XLogP33.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass410.09119807
Monoisotopic Mass410.09119807
Topological Polar Surface Area68.7 Ų
Heavy Atom Count28
Formal Charge0
Complexity618
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA6938-1Abeprazan
MBS5765981Abeprazan hydrochloride
AR-A04906-01Abeprazan HCl
AR-A04908-01Abeprazan Dimer
HY-109079A-01Abeprazan (hydrochloride)
RM-A022603-01Abeprazan Impurity 3
RM-A022601-01Abeprazan Impurity 1
RM-A022602-01Abeprazan Impurity 2
AR-A05203-01Abeprazan-13C-d3
AR-A05205-01N-Nitroso Abeprazan

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