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LSN2839567

CAT: 0931-T10220-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T10220-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1231930-57-6
Target
Drug Metabolite, CDK
Related Pathways
Metabolism, Cell Cycle/Checkpoint
Purity
0.9914
Bioactivity
LSN2839567 (Abemaciclib metabolite M2) is the active metabolite of Abemaciclib, a potent CDK4 and CDK6 inhibitor (IC50s: 1-3 nM) with anticancer activity.LSN2839567 inhibits CDK9.LSN2839567 inhibits cell growth and cell cycle progression in a concentration-dependent manner. cell growth and cell cycle progression in a concentration-dependent manner and can be used to study breast and lung cancer.
Smiles
CC(C)n1c(C)nc2c(F)cc(cc12)-c1nc(Nc2ccc(CN3CCNCC3)cn2)ncc1F
Molecular Formula
C25H28F2N8
Molecular Weight
478.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19206573-01LSN2839567

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