LSN2839567

• Target :

  Drug Metabolite|||CDK

• Related Pathways :

  Metabolism|||Cell Cycle/Checkpoint

• Purity :

  0.9914

• Bioactivity :

  LSN2839567 (Abemaciclib metabolite M2) is the active metabolite of Abemaciclib, a potent CDK4 and CDK6 inhibitor (IC50s: 1-3 nM) with anticancer activity.LSN2839567 inhibits CDK9.LSN2839567 inhibits cell growth and cell cycle progression in a concentration-dependent manner. cell growth and cell cycle progression in a concentration-dependent manner and can be used to study breast and lung cancer.

• Smiles :

  CC(C)n1c(C)nc2c(F)cc(cc12)-c1nc(Nc2ccc(CN3CCNCC3)cn2)ncc1F

• Molecular Formula :

  C25H28F2N8

• Molecular Weight :

  478.54

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1231930-57-6