LSN2839567

• Target:

  Drug Metabolite|||CDK

• Related Pathways:

  Metabolism|||Cell Cycle/Checkpoint

• Purity:

  0.9914

• Bioactivity:

  LSN2839567 (Abemaciclib metabolite M2) is the active metabolite of Abemaciclib, a potent CDK4 and CDK6 inhibitor (IC50s: 1-3 nM) with anticancer activity.LSN2839567 inhibits CDK9.LSN2839567 inhibits cell growth and cell cycle progression in a concentration-dependent manner. cell growth and cell cycle progression in a concentration-dependent manner and can be used to study breast and lung cancer.

• Smiles:

  CC (C) n1c (C) nc2c (F) cc (cc12) -c1nc (Nc2ccc (CN3CCNCC3) cn2) ncc1F

• Molecular Formula:

  C25H28F2N8

• Molecular Weight:

  478.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1231930-57-6