Aβ42-IN-1

CAT: 0931-T10211-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T10211-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2582757-69-3

Target

Others, Gamma-secretase

Related Pathways

Neuroscience, Others, Stem Cells, Proteases/Proteasome

Bioactivity

Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM) . Aβ42-IN-1 potently reduced Aβ42 levels with an IC 50 value of 0.091 μM in cultured cells without inhibiting CYP3A4. Aβ42-IN-1 shows a sustained pharmacokinetic profile.

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O=C(C1=NC=C(C2=C(C)N=C3C(OCC4=CC=C(C5=CC=CC=C5)C=C4)=CC=CN32)C=C1)NCC.[H]Cl

Molecular Formula

C29H27ClN4O2

Molecular Weight

499

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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TD-BP029747	Aβ1-42
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Aβ42-IN-1

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