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A 1070722

CAT: 0931-T10202-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T10202-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1384424-80-9
Target
GSK-3
Related Pathways
PI3K/Akt/mTOR signaling, Stem Cells
Purity
0.999
Bioactivity
A 1070722 is a potent and selective GSK-3 inhibitor, exhibiting high affinity for both GSK-3α (Ki = 0.6 nM) and GSK-3β (Ki = 0.6 nM) . It can penetrate the blood-brain barrier (BBB) and accumulate in brain regions, indicating potential use as a PET radiotracer for quantifying GSK-3 in the brain.
Smiles
COc1ccc2c(NC(=O)Nc3cccc(n3)C(F)(F)F)ccnc2c1
Molecular Formula
C17H13F3N4O2
Molecular Weight
362.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
B7665-50A 1070722
A19973-100A 1070722 100mg
A19973-5A 1070722 5mg
A19973-25A 1070722 25mg
A19973-50A 1070722 50mg
A19973-10A 1070722 10mg
A19973-10mM-DA 1070722 10mM * 1mL in DMSO

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