Voruciclib

• Target :

  CDK

• Related Pathways :

  Cell Cycle/Checkpoint

• Purity :

  0.9999

• Bioactivity :

  Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM) that represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma and effectively blocks CDK9, the transcriptional regulator of MCL-1.

• Smiles :

  CN1CC[C@H]([C@@H]1CO)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1Cl)C(F)(F)F

• Molecular Formula :

  C22H19ClF3NO5

• Molecular Weight :

  469.84

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1000023-04-0