Voruciclib

• Target:

  CDK

• Related Pathways:

  Cell Cycle/Checkpoint

• Purity:

  0.9999

• Bioactivity:

  Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM) that represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma and effectively blocks CDK9, the transcriptional regulator of MCL-1.

• Smiles:

  CN1CC[C@H] ([C@@H]1CO) c1c (O) cc (O) c2c1oc (cc2=O) -c1ccc (cc1Cl) C (F) (F) F

• Molecular Formula:

  C22H19ClF3NO5

• Molecular Weight:

  469.84

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1000023-04-0