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Cyclosporin A

CAT: 0931-T0945-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T0945-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
59865-13-3
Target
Phosphatase, Complement System, Antibiotic
Related Pathways
Microbiology/Virology, Metabolism, Immunology/Inflammation
Purity
0.9999
Bioactivity
Cyclosporin A is a natural product and an active fungal metabolite, classified as a cyclic polypeptide immunosuppressant. It binds to cyclophilin and inhibits the activity of calcineurin (IC50 = 7 nM) as well as CD11a/CD18 adhesion molecules. It is commonly used to induce uremia models.
Smiles
[C@H]([C@@H](C/C=C/C)C)(O)[C@@]1(N(C)C(=O)[C@H]([C@@H](C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H]([C@H](C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@H](CC)NC1=O)[H]
Molecular Formula
C62H111N11O12
Molecular Weight
1202.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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