Salinomycin

• Target:

  Autophagy|||Mitophagy|||Parasite|||Apoptosis|||Antibacterial|||Wnt/beta-catenin|||Antibiotic

• Related Pathways:

  Microbiology/Virology|||Cytoskeletal Signaling|||Stem Cells|||Apoptosis|||Autophagy

• Purity:

  0.98

• Bioactivity:

  Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, specifically inhibits the growth of gram-positive bacteria, acts as a potent inhibitor of Wnt/?-catenin signaling by blocking Wnt-induced LRP6 phosphorylation, and demonstrates selective activity against human cancer stem cells.

• Smiles:

  [H][C@@]1 (CC[C@H] (C) [C@@] ([H]) (O1) [C@@H] (C) [C@H] (O) [C@H] (C) C (=O) [C@H] (CC) [C@@]1 ([H]) O[C@@]2 (O[C@@]3 (CC[C@] (C) (O3) [C@@]3 ([H]) CC[C@] (O) (CC) [C@H] (C) O3) [C@H] (O) C=C2) [C@H] (C) C[C@@H]1C) [C@@H] (CC) C (O) =O

• Molecular Formula:

  C42H70O11

• Molecular Weight:

  751

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  53003-10-4