Lenvatinib

• CAS Number :

  417716-92-8

• Target :

  C-RET|||VEGFR|||FGFR|||PDGFR|||c-Kit

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Apoptosis|||Angiogenesis

• Purity :

  0.9996

• Bioactivity :

  Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity. Lenvatinib has the strongest inhibitory activity on VEGFR2 and VEGFR3 (IC50=4/5.2 nM) . Lenvatinib has strong anti-tumor activity.

• Smiles :

  O(C=1C2=C(C=C(OC)C(C(N)=O)=C2)N=CC1)C3=CC(Cl)=C(NC(NC4CC4)=O)C=C3

• Molecular Formula :

  C21H19ClN4O4

• Molecular Weight :

  426.85

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C