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Indomethacin

CAT: 0931-T0458-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0931-T0458-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
53-86-1
Target
PDE, Autophagy, COX, Phospholipase
Related Pathways
Immunology/Inflammation, Metabolism, Autophagy, Neuroscience
Purity
0.9984
Bioactivity
Indomethacin is an orally active nonsteroidal anti-inflammatory drug (NSAID) that non-selectively inhibits cyclooxygenase enzymes COX-1 and COX-2, with IC50 values of 18 nM and 26 nM, respectively. It exhibits good blood-brain barrier permeability and shows significant anti-inflammatory, anti-tumor, and anti-infective activities. Indomethacin is widely used in research related to cancer, inflammation, and viral infections, and is also commonly used to induce gastric ulcer models in animals.
Smiles
COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(O)=O
Molecular Formula
C19H16ClNO4
Molecular Weight
357.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
112091NO-Indomethacin
TRC-I641000-1GIndomethacin

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