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Zonisamide

CAT: 0931-T0267-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T0267-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
68291-97-4
Target
Sodium Channel, Calcium Channel, Apoptosis, Carbonic Anhydrase
Related Pathways
Apoptosis, Metabolism, Membrane transporter/Ion channel
Purity
>99.99%
Bioactivity
Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms of action. Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels results in a reduction of T-type calcium channel currents, or by binding allosterically to GABA receptors. This latter action may lower the uptake of the inhibitory neurotransmitter GABA while increasing the uptake of the excitatory neurotransmitter glutamate.
Smiles
C(S(N)(=O)=O)C=1C=2C(ON1)=CC=CC2
Molecular Formula
C8H8N2O3S
Molecular Weight
212.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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