Zonisamide

• Target:

  Sodium Channel|||Calcium Channel|||Apoptosis|||Carbonic Anhydrase

• Related Pathways:

  Apoptosis|||Metabolism|||Membrane transporter/Ion channel

• Purity:

  >99.99%

• Bioactivity:

  Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms of action. Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels results in a reduction of T-type calcium channel currents, or by binding allosterically to GABA receptors. This latter action may lower the uptake of the inhibitory neurotransmitter GABA while increasing the uptake of the excitatory neurotransmitter glutamate.

• Smiles:

  C(S(N)(=O)=O)C=1C=2C(ON1)=CC=CC2

• Molecular Formula:

  C8H8N2O3S

• Molecular Weight:

  212.23

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  68291-97-4