Sitagliptin

CAT: 0931-MF-0003295-01Size: 50 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0003295-01Size:50 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
486460-32-6
Target
DPP-4|||Proteasome|||Autophagy
Related Pathways
Autophagy|||Proteases/Proteasome|||Ubiquitination
Purity
0.9983
Bioactivity
Sitagliptin (MK0431), a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This enzyme-inhibiting drug is used either alone or in combination with metformin or thiazolidinedione for treatment of type 2 diabetes mellitus. The drug can competitively inhibit a protein/enzyme and DPP-4, that leads to an incremental amount of active incretins (GLP-1 and GIP), the diminished amount of release of glucagon and increased release of insulin.
Smiles
N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F
Molecular Formula
C16H15F6N5O
Molecular Weight
407.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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