Pemetrexed disodium

CAT: 0931-MF-0003236-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0003236-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
150399-23-8
Target
DNA/RNA Synthesis|||Autophagy|||DHFR|||Apoptosis|||Antifolate
Related Pathways
Apoptosis|||Metabolism|||Autophagy|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Purity
0.9992
Bioactivity
Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has been associated with moderate rates of serum enzyme elevations during therapy, but has not been convincingly linked to instances of acute, clinically apparent liver injury.
Smiles
[Na+].[Na+].Nc1nc2[nH]cc(CCc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)c2c(=O)[nH]1
Molecular Formula
C20H19N5Na2O6
Molecular Weight
471.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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