Etoposide

• Target:

  Autophagy|||Mitophagy|||Apoptosis|||Antibacterial|||Topoisomerase|||Antibiotic

• Related Pathways:

  Apoptosis|||Autophagy|||Microbiology/Virology|||DNA Damage/DNA Repair

• Purity:

  0.9995

• Bioactivity:

  Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 ?M) . Etoposide has antitumor activity and induces apoptosis and autophagy.

• Smiles:

  O=C1[C@@]2([C@@H](C=3C([C@@H](O[C@@H]4O[C@]5([C@]([C@H](O)[C@H]4O)(O[C@H](C)OC5)[H])[H])[C@]2(CO1)[H])=CC6=C(C3)OCO6)C7=CC(OC)=C(O)C(OC)=C7)[H]

• Molecular Formula:

  C29H32O13

• Molecular Weight:

  588.56

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  33419-42-0