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Pazopanib

CAT: 0931-T0097L-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T0097L-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
444731-52-6
Target
Autophagy, VEGFR, FGFR, PDGFR, c-Kit
Related Pathways
Autophagy, Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9985
Bioactivity
Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms (IC50=10/30/47/84/74/140/146 nM) . Pazopanib has antitumor activity.
Smiles
CN(c1ccc2c(C)n(C)nc2c1)c1ccnc(Nc2ccc(C)c(c2)S(N)(=O)=O)n1
Molecular Formula
C21H23N7O2S
Molecular Weight
437.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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