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Cortisone acetate

CAT: 0931-T0034Size: 1 gDry Ice: NoHazardous: No
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CAT#:0931-T0034Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
50-04-4
Target
Endogenous Metabolite, Glucocorticoid Receptor
Related Pathways
Endocrinology/Hormones, Metabolism
Purity
0.9973
Bioactivity
Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate (NSC-49420) diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA transcription. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators.
Smiles
[H][C@@]12CC[C@](O)(C(=O)COC(C)=O)[C@@]1(C)CC(=O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
Molecular Formula
C23H30O6
Molecular Weight
402.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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