Cortisone acetate

• CAS Number :

  50-04-4

• Target :

  Endogenous Metabolite|||Glucocorticoid Receptor

• Related Pathways :

  Endocrinology/Hormones|||Metabolism

• Purity :

  0.9973

• Bioactivity :

  Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate (NSC-49420) diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA transcription. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators.

• Smiles :

  [H][C@@]12CC[C@](O)(C(=O)COC(C)=O)[C@@]1(C)CC(=O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C

• Molecular Formula :

  C23H30O6

• Molecular Weight :

  402.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C