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GK187

CAT: 0804-HY-125986-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-125986-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GK187 is a potent and selective Group VIA calcium-independent phospholipase A2 (GVIA iPLA2) inhibitor with an XI (50) value of 0.0001. GK187 can be used for researching various neurological disorders[1]. [The XI (50) is the mole fraction of the inhibitor in the total substrate interface required to inhibit the enzyme by 50%.]
CAS Number
1071001-50-7
UNSPSC
12352005
Hazard Statement
H225-H302-H319-H336
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gk187.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CCCCC1=CC=C(OC)C=C1)C(F)(F)C(F)(F)F
Molecular Formula
C14H15F5O2
Molecular Weight
310.26
Precautions
P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P330-P370+P378-P403+P233-P403+P235-P405-P501
References & Citations
[1]Magrioti V, et al. New potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2. Bioorg Med Chem. 2013 Sep 15;21 (18) :5823-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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