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Malacidin A

CAT: 0804-HY-N10584Size: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-N10584Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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UNSPSC Description
Malacidin A is the calcium-dependent antibiotic (CDAs). Malacidin A is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria[1][2].
Target Antigen
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/malacidin-a.html
Solubility
10 mM in DMSO
Smiles
O=C1N2[C@@](C(N[C@@H]([C@@H](C(N[C@@H](C(N[C@H](C(N[C@@](C(N[C@H](C(NCC(N[C@@H](C(N[C@H]1C(C)C)=O)[C@H](C)C(O)=O)=O)=O)CC(O)=O)=O)([H])[C@@H](O)C(O)=O)=O)CCCCN)=O)C(C)C)=O)NC([C@H]([C@H](C)C(O)=O)NC(/C=C/C=C\CCC(C)C)=O)=O)C)=O)([H])C[C@H](C2)C
Molecular Weight
1249.37
References & Citations
[1]Hover BM, et, al. Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens. Nat Microbiol. 2018 Apr;3(4):415-422.|[2]Kovalenko N, et, al. A Concise Synthetic Strategy Towards the Novel Calcium-dependent Lipopeptide Antibiotic, Malacidin A and Analogues. Front Chem. 2021 Aug 4;9:687875.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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