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Recombinant SOX9 Antibody

CAT: 0013-GTR18575223Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18575223Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.
UniProt
P48436
Reactivity
Human
Immunogen
A portion of amino acids 393-508 from the human protein was used as the immunogen for the recombinant SOX9 antibody.
Clonality
Recombinant
Clone
SOX9/3916R
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Purification
Protein A affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant SOX9 antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Rabbit
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Rabbit IgG

UniProtKB · P48436

Transcription factor SOX-9

SOX9_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P48436
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SOX9
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q53Y80
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-binding

Biological process

DifferentiationTranscriptionTranscription regulation

Disease

Disease variant

Cellular component

Nucleus

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