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C-Myc Antibody

CAT: 0013-GTR18575191Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18575191Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
It recognizes a transcription factor of 64-67kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.
UniProt
P01106
Reactivity
Human
Immunogen
Amino acids AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA from C-terminus of the human protein was used as the immunogen for the c-Myc antibody. The epitope has been mapped to amino acids EQKLISEEDL.
Clonality
Monoclonal
Clone
9E11.
Conjugation
Unconjugated
Field of Research
Cancer Biology
Purification
Protein G affinity chromatography
Dilution
ELISA: order Ab without BSA for coating
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the c-Myc antibody should be determined by the researcher.
Tested Applications
ELISA
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

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