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Recombinant Villin Antibody

CAT: 0013-GTR18575163Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18575163Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recognizes a protein of 95kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.
UniProt
P09327
Reactivity
Human
Immunogen
A portion of amino acids 600-700 from the human protein was used as the immunogen for the recombinant Villin antibody.
Clonality
Recombinant
Clone
VIL1/4107R
Conjugation
Unconjugated
Purification
Protein A affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant Villin antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Rabbit
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Rabbit IgG

UniProtKB · P09327

Villin-1

VILI_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P09327
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
VIL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R9A7, Q53S11, Q96AC8
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

Actin cappingActin-binding

Coding sequence diversity

Alternative splicing

Biological process

Apoptosis

Ligand

Calcium

Cellular component

Cell projectionCytoplasmCytoskeleton

PTM

Phosphoprotein

Domain

Repeat

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Alternative Products

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bsm-54212R-01Villin Recombinant Antibody
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AN301684L-01Recombinant Villin Monoclonal Antibody
MBS4160516-01SensiStain Anti-Recombinant Villin Antibody
AN300429PRecombinant Ezrin/villin 2 Monoclonal Antibody
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MBS4382295-01Villin (GI-Mucosal & Urogenital Brush Border Marker) Recombinant Rabbit Monoclonal Antibody [Clone VIL1/4107R]
12-1264-20Anti-Villin (GI-Mucosal & Urogenital Brush Border Marker) Recombinant Mouse Monoclonal Antibody (Clone:rVIL1/1325)
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