CD3e Antibody

CAT: 0013-GTR18575051Size: 100 µgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR18575051Size:100 µg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. It is found on all mature T-lymphocytes, NK, T-cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation. It is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. This MAb has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection.

UniProt

P07766

Reactivity

Human

Immunogen

Human PBMC were used as the immunogen for the CD3e antibody.

Clonality

Monoclonal

Clone

OKT3

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Protein G affinity chromatography

Dilution

Flow cytometry: 1-2ug/10^6 cells, Immunohistochemistry (acetone fixed frozen sections), Immunofluorescence: 1-2ug/ml, Functional Studies (order BSA/azide-free format)

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the CD3e antibody should be determined by the researcher.

Tested Applications

FACS, Functional Studies, ICC, IF

Host or Source

Mouse

Preservative

1 mg/ml in 1X PBS; rAlbumin free, sodium azide free

Isotype

Mouse IgG2a, kappa

Related Products

Catalog	Name
GTR18572325	CD3 Antibody / CD3e
GTR18081155-01	CD3 Antibody / CD3e
GTR18317661-01	CD3E Biosimilar Antibody
GTR18406109-01	CD3E Biosimilar Antibody
GTR18579047-01	CD3E Biosimilar Antibody
GTR18795786-01	CD3e Biosimilar Antibody
GTR18290675-01	CD3e monoclonal antibody
GTR18580035	CD3E Biosimilar Antibody
GTR18579359-01	CD3E Biosimilar Antibody
GTR18579250-01	CD3E Biosimilar Antibody

Alternative Products

Catalog	Name
FNab01458	CD3E antibody

CD3e Antibody

Related Products

Alternative Products

Popular Products