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Ochromycinone

CAT: 0804-HY-18061-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-18061-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ochromycinone ((Rac) -STA-21) is a natural antibiotic and a STAT3 inhibitor. Ochromycinone can inhibits STAT3 DNA binding activity, STAT3 dimerization. Ochromycinone has anticancer and antimicrobial activity[1][2].
CAS Number
111540-00-2
Product Name Alternative
(Rac) -STA-21
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial; STAT
Type
Natural Products
Related Pathways
Anti-infection; JAK/STAT Signaling; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/ochromycinone.html
Purity
98.29
Solubility
DMSO : 16.67 mg/mL (ultrasonic)
Smiles
CC(CC1=O)CC2=C1C3=C(C=C2)C(C4=C(O)C=CC=C4C3=O)=O
Molecular Formula
C19H14O4
Molecular Weight
306.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Song H, et al. A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells. Proc Natl Acad Sci U S A. 2005 Mar 29;102 (13) :4700-5.|[2]Nataliya I. Kalinovskaya, et al. New Angucyclinones from the Marine Mollusk Associated Actinomycete Saccharothrix espanaensis An 113. Natural product communications. 2008, 3 (10) :1611-1616.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
STAT3

Alternative Products

CatalogName
FO26492Ochromycinone
LEA54000-01Ochromycinone (STA-21)
MBS6094101-01Ochromycinone ((S) -Ochromycinone, (+) -Ochromycinone, Deoxytetrangomycin, STA-21_x000B_ (3S) -3,4-Dihydro-8-hydroxy-3-methyl-Benz[a]anthracene-1,7,12 (2H) -trione)

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