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FOLH1 Antibody

CAT: 0013-GTR18575152Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18575152Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Folate hydrolase 1 (FOLH1), also known as Prostate-specific membrane antigen (PSMA), is a type II transmembrane glycoprotein belonging to the M28 peptidase family. FOLH1 has two enzymatic activities, one as a prostate-specific integral membrane folate hydrolase and the other as a carboxypeptidase In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer.
UniProt
Q04609
Reactivity
Human
Immunogen
A portion of amino acids 44-177 from the human protein was used as the immunogen for the FOLH1 antibody.
Clonality
Monoclonal
Clone
FOLH1/3734
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Dilution
Western blot: 1-2ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the FOLH1 antibody should be determined by the researcher.
Tested Applications
IHC-P, WB
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

UniProtKB · Q04609

Glutamate carboxypeptidase 2

FOLH1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q04609
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FOLH1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.17.21
Processing
—
Secondary accessions
A4UU12, A9CB79, B7Z312, B7Z343, D3DQS5, E9PDX8, O43748, Q16305, Q541A4, Q8TAY3, Q9NP15, Q9NYE2, Q9P1P8
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumMetal-bindingZinc

Molecular function

CarboxypeptidaseDipeptidaseHydrolaseMetalloproteaseMultifunctional enzymeProtease

Cellular component

Cell membraneCytoplasmMembrane

PTM

GlycoproteinPhosphoprotein

Domain

Signal-anchorTransmembraneTransmembrane helix

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