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CD105 Antibody

CAT: 0013-GTR18575115Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18575115Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity) . May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity) . May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. [UniProt]
UniProt
P17813
Reactivity
Human
Immunogen
Amino acids 74-251 were used as the immunogen for the CD105 antibody.
Clonality
Monoclonal
Clone
CDLA105-1
Conjugation
Unconjugated
Field of Research
Cardiovascular Research; Immunology & Inflammation
Purification
Protein G affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The stated application concentrations are suggested starting points. Titration of the CD105 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG2b, kappa

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