Human CellExp™ CD8b, Human Recombinant

CAT: 0026-P1244-1000Size: 1 mgDry Ice: NoHazardous: No
CAT#:0026-P1244-1000Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
The T-cell surface glycoprotein CD8 beta chain, also called CD8 beta (CD8b), P37 or LEU2 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. It plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Being a member of functional coreceptors, CD8 functions either as a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. In T-cells, CD8b functions primarily as a coreceptor for class I MHC molecules. It initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of cytotoxic T-lymphocytes (CTLs). Additionally, CD8b plays a critical role in thymic selection of CD8+ T-cells. CD8b is thought to play a role in the process of T-cell mediated killing.
CAS Number
9000-83-3
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
12 months

Related Products

CatalogName
P1109-10Human CellExp™ CD83, Human recombinant
P1109-50Human CellExp™ CD83, Human recombinant
7383-50Human CellExp™ CD80, human recombinant
7383-10Human CellExp™ CD80, human recombinant
P1642-50Human CellExp™ CD89 Protein, Human Recombinant
P1642-20Human CellExp™ CD89 Protein, Human Recombinant
7378-10Human CellExp™ CD84 / SLAMF5, human recombinant
7378-50Human CellExp™ CD84 / SLAMF5, human recombinant
7320-100CD8B, human recombinant
7372-20Human CellExp™ CD87 / uPAR / PLAUR, human recombinant

Alternative Products

CatalogName
Pr22477-01Recombinant Human CD8B
rAP-0081CD8B Human Recombinant
MBS8248742-01Recombinant Human CD8B Protein
TP726634CD8B Human Recombinant Protein
PPT-11698Human CD8B Recombinant Protein
RP037924CD8B Recombinant Protein (Human)
MBS147297-01Recombinant Human CD8B, Sf9
GT15682APC anti-human CD8b Recombinant
GT15680PE anti-human CD8b Recombinant
PHH0379-01Recombinant Human CD8B (C-6His)

Popular Products