Phosphogluconate dehydrogenase, human recombinant

CAT: 0026-P1051-10Size: 10 µgDry Ice: NoHazardous: No
CAT#:0026-P1051-10Size:10 µg
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Description
PGD (Phosphogluconate dehydrogenase), also known as 6PGD, is a 483 amino acid enzyme that is involved in the pentose phosphate shunt. Pentose is required for nucleic acid biosynthesis and the pentose phosphate cycle is a major source of NADPH. PGD deficiency increases the level of erythrocyte pyruvate kinase (PK) activity and reduces glutathione synthetase (GSH), resulting in hemolysis. Defects in PGD are generally asymptomatic and are inherited in an autosomal dominant fashion. Recombinant human PGD protein, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques
CAS Number
9000-83-3
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
12 months

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