QDPR, human recombinant

CAT: 26-7821-100Size: 100 µgDry Ice: NoHazardous: No
100 µgSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
QDPR is a member of the short-chain dehydrogenases/reductase (SDR) family of enzymes. Functioning as a homodimer, QDPR plays an important role in the recycling of tetrahydrobiopterin (BH4), an essential cofactor for the hydroxylation of the aromatic amino acids (tryptophan, tyrosine and phenylalanine). More specifically, QDPR catalyzes the regeneration of BH4 from quinonoid dihydrobiopterin (qBH2), the product generated from the hydroxylation reactions. Mutations in the gene encoding QDPR can lead to phenylketonuria II. Recombinant human QDPR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
CAS Number
9000-83-3
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
12 months