RegisterLogin

PAK4, Active

CAT: 0026-7707-5Size: 5 µgDry Ice: YesHazardous: No
CAT#:0026-7707-5Size:5 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
PAK4 is a recently identified member of the p21-activated kinases (PAKs) which have been implicated in the regulation of cell morphology, motility and transformation. These serine/threonine kinases are activated by and are effectors of small GTPases, cdc 42 and Rac. PAK4 belongs to the Group II PAKs which also includes PAK5 and PAK6 while Group I PAKs comprise of PAK1, PAK2 and PAK3. PAK4 differs from other members of the PAK family both in sequence and function. PAK4 has been shown to regulate cell morphology and cytoskeletal organization in mammalian cells. PAK4 regulates the activity of LIM kinase 1 which in turn phosphorylates Cofilin leading to cytoskeletal changes. PAK4 can protect cells from apoptosis in response to several different types of stimuli by inhibiting the pro-apoptotic proteins Bad and Caspase 8. PAK4 has been shown to associate with and mediate the downstream signaling of the keratinocyte growth factor receptor. In addition, PAK4 interacts with the β5 integrins and regulates cell migration during engagement of the αvβ5 integrin receptor.
Shipping Conditions
Dry ice
Storage Conditions
-80°C
Shelf Life
12 months

Related Products

CatalogName
7727-5PAK7, Active
3444-100PAK4 Antibody
3444-30TPAK4 Antibody
3444BP-50PAK4 Blocking Peptide
A1973-100Phospho PAK4 (Ser474) Antibody
7738-5CK2a1, Active
7749-5SGK2, Active
7716-5NEK6, Active
7732-5BMX, Active
7702-5Akt2, Active

Alternative Products

CatalogName
MBS517364-01PAK4, Active
167933PAK4, Active, Recombinant, Human (pak-4, pak 4, Active PAK4, PDK4, human PDK4, active kinase, active kinases, PDK, recombinant PDK4, recombinant PDK, kinase activity assay, protein kinase) discontinued
327398-01PAK4
MBS8516520-01PAK4 Antibody
TS402302P5PAK4 CytoSection
UA080113-01PAK4 Protein
T211616-01PAK4-IN-6
T201422-01PAK4-IN-5
DF7078-BPPAK4 Peptide
MBS5806599PAK4-IN-1

Popular Products