Products for Research Use Only
RegisterLogin

Human CellExp™ FOLR1, mouse recombinant

CAT: 0026-7457-10Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0026-7457-10Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Folate Receptor 1 (FOLR1) also known as Folate receptor alpha, Folate Binding Protein (FBP), FOLR, and is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Mature FOLR1 is an N-glycosylated protein that is anchored to the cell surface by a GPI linkage. FOLR1 is predominantly expressed on epithelial cells and is dramatically upregulated on many carcinomas. FOLR1 is internalized to the endosomal system where it dissociates from its ligand before recycling to the cell surface. A soluble form of FOLR1 can be proteolytically shed from the cell surface into the serum and breast milk. Defects in FOLR1 are the cause of neurodegeneration due to cerebral folate transport deficiency (NCFTD). NCFTD is an autosomal recessive disorder resulting from brain-specific folate deficiency early in life.
CAS Number
9000-83-3
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
12 months

Related Products

CatalogName
7456-50Human CellExp™ FOLR1, human recombinant
7456-10Human CellExp™ FOLR1, human recombinant
P1340-10Human CellExp™ FOLR1, Rhesus macaque Recombinant
P1340-50Human CellExp™ FOLR1, Rhesus macaque Recombinant
P1339-50Human CellExp™ FOLR1, Fc Tag, Human Recombinant
P1339-10Human CellExp™ FOLR1, Fc Tag, Human Recombinant
7471-50Human CellExp™ FOLR2, human recombinant
7471-10Human CellExp™ FOLR2, human recombinant
P1163-50Human CellExp™ DLL4, Mouse Recombinant
7268-10Human CellExp™ LIF, mouse recombinant

Alternative Products

CatalogName
MBS7621925-01Recombinant Mouse FOLR1
RP134978FOLR1 Recombinant Protein (Mouse)
PPT-16527Mouse FOLR1 Recombinant Protein
6936-FR-050Recombinant Mouse FOLR1 CF
TP727052Folr1 Mouse Recombinant Protein
GTR19125602-01Recombinant Mouse FOLR1 Protein
PHM0680-01Recombinant Mouse FOLR1 (C-6His)
TMPY-01803-01FOLR1 Protein, Mouse, Recombinant (His)
MBS1579060-01Recombinant Mouse FOLR1 Protein, N-His
MBS961553-01Recombinant Mouse Folate receptor alpha (Folr1)

Popular Products