RegisterLogin

Sox2, human recombinant

CAT: 0026-7202-10Size: 10 µgDry Ice: NoHazardous: No
CAT#:0026-7202-10Size:10 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Sox2, also known as sex determining region Y (SRY)-box 2, belongs to a diverse family of structurally-related transcription factors whose primary structure contains a 79-residue DNA-binding domain, called high mobility group (HMG) box. It plays an essential role in maintaining the pluripotency of embryonic stem cells (ESC) and determination of cell fate. Microarray analysis showed that Sox2 regulates the expression of multiple genes involved in embryonic development including FGF-4, YES1 and ZFP206. Sox2 acts as a transcriptional activator after forming a ternary complex with Oct3/4 and a conserved non-coding DNA sequence (CNS1) located approximately 2 kb upstream of the RAX promoter. The introduction of Sox2, Oct4, Myc, and Klf4, into human dermal fibroblasts isolated from a skin biopsy of a healthy research fellow was sufficient to confer a pluripotent state upon the fibroblast genome. The reprogrammed cells thus obtained resemble ESC in morphology, gene expression, and in the capacity to form teratomas in immune-deficient mice. Recombinant human Sox2 is a 34.3 kDa protein containing 317 amino-acid residues.
CAS Number
9000-83-3
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
12 months

Related Products

CatalogName
7203-10Sox2-TAT, human recombinant
7203-50Sox2-TAT, human recombinant
K4199-100SOX2 (Human) ELISA Kit
4160-1000Survivin, human recombinant
4507-100FABP7, human recombinant
6317-100Human Recombinant PPIL1
4759-1000Endostatin, human recombinant
4760-5000ApoE2, human recombinant
4675-50Noggin, human recombinant
7333-100ULBP1, human recombinant

Alternative Products

CatalogName
MBS7616053-01Recombinant Human SOX2
P7235-100μgRecombinant Human SOX2-TAT
NBP1-41144Recombinant Human SOX2 Protein
PROTP48431-100ugHuman SOX2 Recombinant Protein
OPCA03959-20UGSOX2 Recombinant Protein (Human)
TP300757SOX2 (NM_003106) Human Recombinant Protein
NBP2-35268-1mgRecombinant Human SOX2 TAT Protein
MBS1574085-01Recombinant Human SOX2, N-His
YP-W11147-01Human SOX2 (SOX2) ELISA Kit
HY-P701993-01Sox2, Human

Popular Products