PDGF-CC, human recombinant

CAT: 0026-7183-50Size: 50 µgDry Ice: NoHazardous: No
CAT#:0026-7183-50Size:50 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
The platelet-derived growth factor (PDGF) family of heparin-binding growth factors consists of five known members, denoted PDGF-AA, PDGF-BB, PDGF-AB, PDGF-CC and PDGF-DD. The mature and active form of these proteins, an anti-parallel disulfide-linked dimer of two 12-14 kDa polypeptide chains, is obtained through proteolytic processing of biologically inactive precursor proteins, which contain an N-terminal CUB domain and a PDGF/VEGF homologous domain. The PDGFs interact with two related protein tyrosine kinase receptors, PDGFR-α and PDGFR-β, and are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and certain tumor cells. They play an important role in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubules epithelial cell development. Mature PDGFs are stored in platelet α-granules and are released upon platelet activation. PDGF-AA, -AB, -BB and –CC signal primarily through the PDGF-Rα receptor, whereas PDGF-DD interacts almost exclusively with the PDGF-Rβ receptor. Recombinant human PDGF-CC is a 25kDa protein consisting of two identical disulfide-linked 112 amino-acid polypeptide chains.
CAS Number
9000-83-3
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
12 months

Related Products

CatalogName
4488-50PDGF-BB, human recombinant
4488-1000PDGF-BB, human recombinant
4488-10PDGF-BB, human recombinant
4482-10PDGF-AA, human recombinant
4485-50PDGF-AB, human recombinant
4482-50PDGF-AA, human recombinant
4482-1000PDGF-AA, human recombinant
4485-1000PDGF-AB, human recombinant
4485-10PDGF-AB, human recombinant
6476-10Human CellExp™ PDGF-AA, Human Recombinant

Alternative Products

CatalogName
1687-CC-025Recombinant Human PDGF-CC
PROTQ9NRA1-1Recombinant Human PDGF-CC Protein
1687-CC-025/CFRecombinant Human PDGF-CC CF
MF-0131865-01PDGF-CC Protein, Human, Recombinant
MBS651088-01Platelet Derived Growth Factor CC, Recombinant, Human (PDGF-CC)
MBS8433110-01Human PDGF-CC Recombinant Protein Lyophilized
220176Platelet Derived Growth Factor CC, Recombinant, Human (PDGF-CC) discontinued
IHUPDGFCCRLY5UGHuman PDGF-CC Recombinant Protein Lyophilized 5UG
QP10806-1mgRecombinant Human PDGF CC Protein, His, E.coli-1mg
QP10806-5ugRecombinant Human PDGF CC Protein, His, E.coli-5ug

Popular Products