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IL-36β, Human Recombinant

CAT: 0026-7110-10Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0026-7110-10Size:10 µg
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Description
The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36β is highly expressed in psoriatic plaques, and at lower levels in various other tissues. IL-36β signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36β also functions as an agonist of NF-kappaB, and stimulates the production of pro-inflammatory proteins, including IL-6, IL-8, BD-2, and BD-3. Recombinant human IL-36β is a 17.3 kDa protein containing 154 amino acid residues.
CAS Number
9000-83-3
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
12 months

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