Human Recombinant Ubiquitin-K63

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: Yes

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CAT:

26-6497-500

Size:

500 µg

Price:

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For price, please contact [email protected].

Human Recombinant Ubiquitin-K63

Description: Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this initial ubiquitin, utilizing any one of the seven lysine residues on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation. This tag-free recombinant form of human ubiquitin is engineered to have all available lysines mutated to arginines, except at position 63. This molecule, therefore, can only form polyubiquitin chains of K63 linkage type. Covalent attachment of ubiquitin to other proteins serves various functions, but its major role is to target cellular proteins for destruction. Cellular components that activate, transfer, remove, or simply recognize ubiquitin number in the hundreds, perhaps even in the thousands. In light of this complexity the ubiquitin pathway is ideal for a systems biology approach. Ubiquitin plays a very important role in regulated non-lysosomal ATP dependent protein degradation. The Ub-proteasome proteolytic pathway, which is a complex process, is implicated to be of great importance for regulating numerous cellular processes.
Shipping Conditions: Dry ice
Storage Conditions: -80°C
Shelf Life: 12 months

Complementary Product Range

Our range of products, including Human Recombinant Ubiquitin-K63, falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

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Cat	Name
6497-1000	Human Recombinant Ubiquitin-K63
6497-500	Human Recombinant Ubiquitin-K63
6419-50	K63-linked Tri-Ubiquitin
6418-50	K63-linked Di-Ubiquitin
6420-25	K63-linked Tetra-Ubiquitin
4841-100	Ubiquitin, human recombinant
4841-1000	Ubiquitin, human recombinant
6395-500	Human Recombinant Ubiquitin-K6
6396-1000	Human Recombinant Ubiquitin-K11
6397-500	Human Recombinant Ubiquitin-K27