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Human recombinant Ubiquitin Activating Enzyme E1

CAT: 0026-6429-50Size: 50 µgDry Ice: YesHazardous: No
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CAT#:0026-6429-50Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UBE1, the ubiquitin activating enzyme, is the first enzyme utilized in the pathway to conjugate ubiquitin onto target substrates through an ubiquitin-protein isopeptide bond. The C-terminal glycine of an ubiquitin (G76) is initially adenylated in an ATP dependent manner activating it so it can be transferred to the active site cysteine of UBE1 forming an ubiquitin-UBE1 thiolester. With the help of the other enzymes in the ubiquitin conjugation pathway (E2/E3 enzymes) the ubiquitin is transferred to a specific lysine on a target substrate.
CAS Number
9000-83-3
Shipping Conditions
Dry ice
Storage Conditions
-80°C
Shelf Life
12 months

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Alternative Products

CatalogName
407264-01UBA3 (NEDD8-Activating Enzyme E1 Catalytic Subunit, NEDD8-Activating Enzyme E1C, Ubiquitin-Activating Enzyme E1C, Ubiquitin-Like Modifier-Activating Enzyme 3, Ubiquitin-Activating Enzyme 3, UBE1C)
361392-01UBA3 (NEDD8-activating Enzyme E1 Catalytic Subunit, NEDD8-activating Enzyme E1C, Ubiquitin-activating Enzyme E1C, Ubiquitin-like Modifier-activating Enzyme 3, Ubiquitin-activating Enzyme 3, UBE1C) discontinued
U0882-10BUBE1C, CT (Ubiquitin-activating Enzyme E1C, NEDD8-activating Enzyme E1 Catalytic Subunit, Ubiquitin-like Modifier-activating Enzyme 3, Ubiquitin-activating Enzyme 3, NEDD8-activating Enzyme E1C, UBA3)
353320UBE1C (NEDD8-Activating Enzyme E1 Catalytic Subunit, UBA3, Ubiquitin-Activating Enzyme 3, Ubiquitin-Activating Enzyme E1C)
MBS6504441-01UBE1C, CT (Ubiquitin-activating Enzyme E1C, NEDD8-activating Enzyme E1 Catalytic Subunit, Ubiquitin-like Modifier-activating Enzyme 3, Ubiquitin-activating Enzyme 3, NEDD8-activating Enzyme E1C, UBA3) (AP)
MBS6504444-01UBE1C, CT (Ubiquitin-activating Enzyme E1C, NEDD8-activating Enzyme E1 Catalytic Subunit, Ubiquitin-like Modifier-activating Enzyme 3, Ubiquitin-activating Enzyme 3, NEDD8-activating Enzyme E1C, UBA3) (FITC)
MBS6504442-01UBE1C, CT (Ubiquitin-activating Enzyme E1C, NEDD8-activating Enzyme E1 Catalytic Subunit, Ubiquitin-like Modifier-activating Enzyme 3, Ubiquitin-activating Enzyme 3, NEDD8-activating Enzyme E1C, UBA3) (APC)
MBS6504451-01UBE1C, CT (Ubiquitin-activating Enzyme E1C, NEDD8-activating Enzyme E1 Catalytic Subunit, Ubiquitin-like Modifier-activating Enzyme 3, Ubiquitin-activating Enzyme 3, NEDD8-activating Enzyme E1C, UBA3) (PE)
MBS6504443-01UBE1C, CT (Ubiquitin-activating Enzyme E1C, NEDD8-activating Enzyme E1 Catalytic Subunit, Ubiquitin-like Modifier-activating Enzyme 3, Ubiquitin-activating Enzyme 3, NEDD8-activating Enzyme E1C, UBA3) (Biotin)
134983UBA5 (Ubiquitin-like Modifier-activating Enzyme 5, Ubiquitin-activating Enzyme 5, ThiFP1, UFM1-activating Enzyme, Ubiquitin-activating Enzyme E1 Domain-containing Protein 1, UBE1DC1)

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