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Human Recombinant FKBP3

CAT: 0026-6342-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0026-6342-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FKBP3 is part of a family of immunosuppressant receptors which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 accelerates the folding of proteins. FKBP3 is part of the immunophilin protein family, which participates in immunoregulation and fundamental cellular processes concerning protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a greater affinity for rapamycin than for FK506 and therefore is a significant protein for immunosuppression by rapamycin.
CAS Number
9000-83-3
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
12 months