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FLT1, human recombinant

CAT: 0026-4951-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0026-4951-100Size:100 µg
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Description
The flt-1 gene was first described in 1990. The receptor contains seven immunoglobulin-like extracellular domains, a single transmembrane region and an intracellular split tyrosine kinase domain. Compared to VEGFR-2 the Flt-1 receptor has a higher affinity for VEGF but a weaker signaling activity. VEGFR-1 thus leads not to proliferation of endothelial cells, but mediates signals for differentiation. Soluble FLT1 Human Recombinant produced in baculovirus is monomeric, glycosylated, polypeptide containing 688 amino acids and having a molecular mass of 96 kDa. The soluble receptor protein contains only the first 6 extracellular domains, which contain all the information necessary for binding of VEGF. The FLT1 is purified by proprietary chromatographic techniques.
CAS Number
9000-83-3
Shipping Conditions
Blue ice
Storage Conditions
-20°C
Shelf Life
12 months

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