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IGF-BP5, human recombinant

CAT: 0026-4723-25Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0026-4723-25Size:25 µg
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Description
Human IGF-BP5 is a 28.6 kDa cysteine-rich secreted protein produced by Vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Studies show that IGF-BP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGF-BP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole body growth inhibition, and retarded muscle development. Recombinant human IGF-BP5 is a 28.6 kDa protein consisting of 253 amino acid residues.
CAS Number
9000-83-3
Shipping Conditions
Gel pack
Storage Conditions
-20°C
Shelf Life
12 months

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