Products for Research Use Only

Aprotinin

CAT: 0026-4690-100Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0026-4690-100Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. It is present in blood and in most tissues, with a high concentration in lung, inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins. Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids arranged in a single polypeptide chain, cross-linked by three disulfide bridges and having a molecular mass of 6512 Daltons. Aprotinin is purified by proprietary chromatographic techniques.
Shipping Conditions
Gel pack
Storage Conditions
-20°C
Shelf Life
12 months