Products for Research Use Only
RegisterLogin

CD2665

CAT: 0804-HY-107437-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-107437-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CD2665 is an orally active and selective RAR-β, γ antagonist, with Kd values of 306 nM, 110 nM for RAR-β and RAR-γ, repectively[1][3].
CAS Number
170355-78-9
UNSPSC
12352005
Target
RAR/RXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cd2665.html
Purity
99.68
Solubility
DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COCCOCOC1=CC2=CC=C(C3=CC=C(C(O)=O)C=C3)C=C2C=C1C45C[C@H](C6)C[C@H](C[C@H]6C5)C4
Molecular Formula
C31H34O5
Molecular Weight
486.60
References & Citations
[1]Kim MJ, et al. The role of specific retinoid receptors in sebocyte growth and differentiation in culture. J Invest Dermatol. 2000 Feb;114 (2) :349-53. |[2]Alfos S, Boucheron C, et al. A retinoic acid receptor antagonist suppresses brain retinoic acid receptor overexpression and reverses a working memory deficit induced by chronic ethanol consumption in mice. Alcohol Clin Exp Res. 2001 Oct;25 (10) :1506-14.|[3]Koyama E, et al.Premature Growth Plate Closure Caused by a Hedgehog Cancer Drug Is Preventable by Co-Administration of a Retinoid Antagonist in Mice. J Bone Miner Res. 2021 Jul;36 (7) :1387-1402.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P82931-01CD266 Antibody (YA2676, Rabbit)
HY-128977CD235
HY-P81534-01CD276 Antibody (YA1279, Rabbit)
HY-P83666mHuman CD235 Antibody (APC)
HY-P84532-01CD215 Antibody (YA4229, Mouse)
HY-P81605CD276/B7H3 Antibody (YA1350)
HY-P85833-01CD276/B7H3 Antibody (YA5525, Mouse)
HY-P84637-01CD276/B7H3 Antibody (YA4334, Mouse)
HY-P702528-01CD206/MMR, Mouse (HEK293, His)
HY-P81691-01CD226/DNAM1 Antibody (YA1436, Rabbit)

Alternative Products

CatalogName
T14911-01CD2665

Popular Products