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XRK3F2

CAT: 0026-B2381-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B2381-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
XRK3F2 is an inhibitor of the p62-ZZ domain (Sequestosome 1) that inhibits MM cell growth and BMSC growth enhancement of human MM cells. XRK3F2 induces dramatic cortical bone formation that is restricted to MM containing bones and blocks the effects and upregulation of tumor necrosis factor alpha (TNFα), an osteoblast (OB) differentiation inhibitor that is increased in the MM bone marrow microenvironment and utilizes signaling complexes formed on p62-ZZ, in BMSC.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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