MMAE

CAT: 0026-B2344-5Size: 5 mgDry Ice: NoHazardous: No

CAT#:0026-B2344-5Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

MMAE (Monomethyl auristatin E) is a synthetic derivative of dolastatin 10 that functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. Suppresses tumor cell viability in vitro (GIC50 values are 0.22, 0.49 and 0.54 nM in BT474, MDA-MB-361-DYT2 and N87 cells, respectively). It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity.

Shipping Conditions

Gel Pack

Storage Conditions

-20ºC

Shelf Life

36 months

Related Products

Catalog	Name

Alternative Products

Catalog	Name
456396-01	MMAE
T9901A-199-01	Oregovomab MMAE
T9901A-201-01	Praluzatamab MMAE
T9901A-208-01	Ulocuplumab MMAE
T9901A-218-01	Mirvetuximab MMAE
T84799-01	PDS-MMAE
T18312-01	Mc-MMAE
MBS5752979	D8-MMAE
MBS5824232	Depatuxizumab MMAE
C00967-01	Anetumab-MMAE

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