SSE-15206

CAT:

26-B2342-5

Size:

5 mg

Price:

Ask

Description:
SSE-15206 is a pyrazolinethioamide derivative that has potent antiproliferative activities in cancer cell lines of different origins and overcomes resistance to microtubule-targeting agents. Treatment of cells with SSE-15206 causes aberrant mitosis resulting in G2/M arrest due to incomplete spindle formation, a phenotype often associated with drugs that interfere with microtubule dynamics. SSE15206 inhibits microtubule polymerization both in biochemical and cellular assays by binding to colchicine site in tubulin as shown by docking and competition studies.
Shipping Conditions:
Gel Pack
Storage Conditions:
-20ºC
Shelf Life:
36 months

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